Selina: Karen, what do you think of Pierce?
Karen: Well, I think there are pros and cons to every candidate, so we just need to weigh out the pros and cons.
Amy: Have you been sent from the future to destroy me, 'cause it's working! "I think that each candidate has merits and demerits, and I don't know my left buttcheek from my right buttcheek, but I believe in listening to both buttcheeks and then farting out my asshole mouth!" That's not even bullshit! Bullshitting takes talent, you have none! You are just a blah-blah-blah-blah bitch!
Selina: Okay, Amy, that is enough.
Amy: I have bitten my tongue so long, it looks like a dog's cushion. But no more! You have made it impossible to do this job. You have two settings--no decision and bad decision. I wouldn't let you run a bath without having the Coast Guard and the fire department standing by, but yet here you are running America. You are the worst thing that has happened to this country since food in buckets and maybe slavery! I've had enough. I'm gone.
Selina: (as Amy walks to the door) Well, I guess she's finished with her little...(Amy walks back to her) oh, nope, look at that, there's more.
Amy: You have achieved nothing apart from one thing. The fact that you are a woman means we will have no more women presidents because we tried one and she f**king sucked. Goodbye, ma'am.
Quote from S04E05 - Convention